Clear cell sarcoma of the kidney (CCSK) is an extremely rare type of kidney cancer comprising 3% of all pediatric renal tumours. Clear cell sarcoma of the kidney can spread from the kidney to other organs, most commonly the bone, but also including the lungs, brain, and soft tissues of the body.
Despite the similarities in names, clear cell sarcoma of the kidney is unrelated to clear cell sarcoma of soft tissue, also known as malignant melanoma of soft parts.
Video Clear-cell sarcoma of the kidney
Signs and symptoms
Typical gross features include large size (mean diameter 11.3 cm), a mucoid texture, foci of necrosis, and prominent cyst formation.
Maps Clear-cell sarcoma of the kidney
Cause
Research in 2005 showed that CCSK can arise within a renal mesenchymal cell that shows a wide variety of neural markers. Typical presentation is between 1 and 4 years of age, and a 2:1 male-to-female ratio is observed.
Diagnosis
Treatment
2004 research showed that CCSK patients exhibit an improved relapse-free survival from a longer course of therapy when using vincristine, doxorubicin, and dactinomycin, but their long-term survival is unchanged compared with patients receiving 6 months of therapy.
References
Kidney Treatment And Solutions
External links
- Clear cell sarcoma of the kidney entry in the public domain NCI Dictionary of Cancer Terms
This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".
Source of the article : Wikipedia
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